{"id":21733,"date":"2022-05-04T16:49:17","date_gmt":"2022-05-04T16:49:17","guid":{"rendered":"https:\/\/www.hri-research.org\/?p=21733"},"modified":"2022-07-15T15:47:58","modified_gmt":"2022-07-15T15:47:58","slug":"randomised-controlled-trials-data-update-2021","status":"publish","type":"post","link":"https:\/\/www.hri-research.org\/bg\/2022\/05\/randomised-controlled-trials-data-update-2021\/","title":{"rendered":"Randomised controlled trials data update 2021"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">We are pleased to announce the <\/span><span style=\"font-weight: 400;\">findings from Dr Robert Mathie\u2019s <\/span><span style=\"font-weight: 400;\">latest clinical evidence update:<\/span><\/p>\n<p><span style=\"color: #000080;\"><b>Total number of randomised controlled trials (RCTs):<\/b><\/span><br \/>\n<b>2021:\u00a0<\/b>255 RCTs of homeopathic treatments for 136 medical conditions<\/p>\n<p><span style=\"font-weight: 400;\">It is promising to see a slight increase in the volume of trials published per year, i.e. 14 RCTs in 2021, compared to 12 RCTs in 2020.<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"color: #000080;\"><b>Double-blind placebo-controlled trials (DB-RCTs):<br \/>\n<\/b><\/span><span style=\"font-weight: 400;\">Considering only DB-RCTs in humans, published in peer reviewed journals (excluding prophylaxis and cross-over studies), the analysis found<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<p><b>2020<\/b><span style=\"font-weight: 400;\">:\u00a0140 trials\u00a0on 86 different medical conditions<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><b>2021<\/b><span style=\"font-weight: 400;\">:\u00a0<\/span><a href=\"https:\/\/www.hri-research.org\/resources\/homeopathy-faqs\/scientific-evidence-for-homeopathy\/placebo-controlled-trials-of-homeopathic-treatment\/\"><span style=\"font-weight: 400;\">148 trials<\/span><\/a><span style=\"font-weight: 400;\">\u00a0on 88 different medical conditions<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><strong>148 RCTs of homeopathy (end of 2021)\u2029<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-21911 size-full\" src=\"https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226.png\" alt=\"\" width=\"960\" height=\"453\" srcset=\"https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226.png 960w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-300x142.png 300w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-768x362.png 768w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-98x46.png 98w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-198x93.png 198w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-158x75.png 158w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-160x76.png 160w, https:\/\/www.hri-research.org\/wp-content\/uploads\/2022\/05\/2021-RCT-Data-e1651683903226-520x245.png 520w\" sizes=\"auto, (max-width: 960px) 100vw, 960px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">The <strong>8 new DB-RCTs &#8211; 2 positive<\/strong><sup>1,2<\/sup><strong> 0 negative and 6 inconclusive<\/strong><\/span><sup>3-8<\/sup>\u00a0<strong>trials<\/strong> &#8211; have resulted in a slight shift in the overall balance of evidence as follows:<\/p>\n<p><span style=\"font-weight: 400;\">Positive: \u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/span>\u2193<span style=\"font-weight: 400;\"> 1%<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">Negative:\u00a0<\/span>\u00a0 \u00a0 \u00a0 \u2193<span style=\"font-weight: 400;\">\u00a02%<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">Inconclusive<\/span>: \u2191<span style=\"font-weight: 400;\">\u00a02%<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Our most popular\u00a0<\/span><a href=\"https:\/\/www.hri-research.org\/resources\/homeopathy-faqs\/scientific-evidence-for-homeopathy\/\"><span style=\"font-weight: 400;\">FAQ webpage<\/span><\/a><span style=\"font-weight: 400;\">\u00a0has been updated to include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">the new 2021 data on homeopathy trials<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">the\u00a0<\/span><a href=\"https:\/\/www.hri-research.org\/resources\/homeopathy-faqs\/scientific-evidence-for-homeopathy\/placebo-controlled-trials-of-homeopathic-treatment\/\"><span style=\"font-weight: 400;\">full list of references<\/span><\/a><span style=\"font-weight: 400;\"> for the 148 double-blind placebo controlled trials represented in the pie chart.<\/span><\/li>\n<\/ul>\n<p><strong>New DB-RCTs:\u00a0<\/strong><\/p>\n<ol>\n<li style=\"font-weight: 400;\">Ghosh S, Ravindra RK, Modak A\u00a0<em>et al. <\/em>Efficacy of individualized homeopathic medicines in primary dysmenorrhea: a double-blind, randomized, placebo-controlled, clinical trial. <em>J Complement Integr Med<\/em> 2021 Jun 3. doi: 10.1515\/jcim-2020-0512. Online ahead of print.<\/li>\n<li style=\"font-weight: 400;\">Shahid S, Ghosh S, Chakraborty AS<em> et al<\/em>. Efficacy of Individualized Homeopathic Medicines in Plantar Fasciitis: Double-blind, Randomized, Placebo-Controlled Clinical Trial. <em>Homeopathy<\/em> 2021 Sep 07. DOI: 10.1055\/s-0041-1731383. Online ahead of print.<\/li>\n<li style=\"font-weight: 400;\">Dey S, Hashmi S, Saha S <em>et al<\/em>. A Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Individualized Homeopathic Medicines for Cutaneous Warts. <em>Homeopathy<\/em> 2021 Aug;<strong>110(3)<\/strong>:149-159<\/li>\n<li style=\"font-weight: 400;\">Dey S, Shaikh AR, Saha S <em>et al.<\/em> Efficacy of Individualized Homeopathic Medicines in the Treatment of Atopic Dermatitis in Adults: A Double-Blind, Randomized, Placebo-Controlled, Preliminary Trial. <em>Complement Med Res<\/em> 2021 Apr 15;1-10<\/li>\n<li style=\"font-weight: 400;\">Dolev T, Ben-David M, Shahadi I <em>et al<\/em>. Attention Dysregulation in Breast Cancer Patients Following a Complementary Alternative Treatment Routine: A Double-Blind Randomized Trial. <em>Integrative Cancer Therapies<\/em> 2021; 20: 1\u201310<\/li>\n<li style=\"font-weight: 400;\">Dutta S, Ganguly S, Mukherjee SK\u00a0<em>et al.<\/em> Efficacy of individualized homeopathic medicines in intervening with the progression of pre-hypertension to hypertension: A double-blind, randomized, placebo-controlled trial. <em>Explore (NY)<\/em> 2021 Jun 5;S1550-8307(21)00098-7.<\/li>\n<li style=\"font-weight: 400;\">Parewa M, Burman AS, Brahma A\u00a0<em>et al.<\/em> Individualized Homeopathic Medicines in the Treatment of Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled, Pilot Trial. <em>Complement Med Res<\/em> 2021; <strong>28(5)<\/strong>:407-418<\/li>\n<li style=\"font-weight: 400;\">Sadhukhan S, Singh S, Michael J\u00a0<em>et al.<\/em> Individualized Homeopathic Medicines in Stage I Essential Hypertension: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial. <em>J Altern Complement Med<\/em> 2021 Jun; <strong>27(6)<\/strong>:515-521<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>We are pleased to announce the findings from Dr Robert Mathie\u2019s latest clinical evidence update: Total number of randomised controlled trials (RCTs): 2021:\u00a0255 RCTs of homeopathic treatments for 136 medical conditions It is promising to see a slight increase in the volume of trials published per year, i.e. 14 RCTs in 2021, compared to 12 [&hellip;]<\/p>\n","protected":false},"author":835,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[12],"tags":[],"class_list":["post-21733","post","type-post","status-publish","format-standard","hentry","category-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/posts\/21733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/users\/835"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/comments?post=21733"}],"version-history":[{"count":0,"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/posts\/21733\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/media?parent=21733"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/categories?post=21733"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hri-research.org\/bg\/wp-json\/wp\/v2\/tags?post=21733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}